If you're being treated for hypothyroidism, and are one of the many patients who benefit from the addition of T3, there's some good news.
We should eventually see a new form of T3 (liothyronine) hitting the market, and if early news is true, it may be better than the liothyronine (Cytomel) tablets and even compounded sustained release T3 currently available.
Pharmaceutical company Synthonics has been conducting clinical trials of PolyZincLiothyronine (PZL), a specialized extended release form of liothyronine that combines zinc and liothyronine to slowly release the T3 without overstimulation.
Studies showed that the PZL's release was much closer to how a healthy thyroid gland would release T3, compared to other forms of liothyronine.
According to a Synthonic press release, "There is a growing consensus within the medical community as to the benefits an extended release T3 could provide to hypothyroid patients that do not fully benefit from levothyroxine"
"When administered orally, PZL is designed to adhere to the lining of the small intestine where it creates a depot of drug product from which T3 molecules are gradually released and absorbed into the bloodstream. The gradual release of T3 molecules significantly reduces the peaks in circulating T3 levels produced by existing LT3 formulations and produce steady, euthyroid-like T3 levels in the blood of patients with hypothyroidism."
"Dr. Scott Palmer, an assistant professor at Rush Medical College and the chairman of Synthonics’ scientific advisory board, stated that 'a product, such as PZL, that provides stable replacement levels of T3 would represent a dramatic advance in the treatment of hypothyroidism and could significantly improve the health and quality of life of millions that suffer from that disease.'"
Stay tuned for more news on when PZL may be available to hypothyroid patients!
Heads Up: PolyZincLiothyronine (PZL) is Coming!
I would like more info on when this might be available. I think it might be the answer for my continuing Hypothyroidism while taking Cytomel plus NP